Butanethioic acid, 3-oxo-, S-(1,1-dimethylethyl) ester → 2-(4-ethanesulfonylbenzyl)-3-oxothiobutyric acid S-tert-butyl Ester

HRID 2266587Notes

Reaction equation

HRID 2266587 reaction equation
Br[CH2:2][C:3]1[CH:8]=[CH:7][C:6]([S:9]([CH2:12][CH3:13])(=[O:11])=[O:10])=[CH:5][CH:4]=1.[C:14]([S:18][C:19](=[O:24])[CH2:20][C:21](=[O:23])[CH3:22])([CH3:17])([CH3:16])[CH3:15]>>[C:14]([S:18][C:19](=[O:24])[CH:20]([CH2:2][C:3]1[CH:8]=[CH:7][C:6]([S:9]([CH2:12][CH3:13])(=[O:11])=[O:10])=[CH:5][CH:4]=1)[C:21](=[O:23])[CH3:22])([CH3:17])([CH3:15])[CH3:16]

Participants

3

Reactant 2

HCID 140007Butanethioic acid, 3-oxo-, S-(1,1-dimethylethyl) esterHCID 672188351-(Bromomethyl)-4-(ethanesulfonyl)benzene

Product 1

HCID 866314562-(4-ethanesulfonylbenzyl)-3-oxothiobutyric acid S-tert-butyl Ester

Procedure

The title compound was prepared by the method of Preparation 34a using 1-bromomethyl-4-ethanesulfonylbenzene and 3-oxothiobutyric acid S-tert-butyl ester.

Sources & evidence

ORD record
ord-fe8edca495b9499591c00923d483e9fc
Source dataset
uspto-grants-2010_12
Patent number
US07858640B2

Reaction notes

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