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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2266609Generated: November 2, 2026

Methyl 2-bromopropionate → 2-[3-(2,4-dichlorobenzyl)-8-fluoro-4-methyl-2-oxo-1,2-dihydroquinolin-5-yloxy]propionic Acid Methyl Ester

https://huagongshe.com/reaction/2266609

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-bromopropionateHCID 95576—
Reactant3-(2,4-dichlorobenzyl)-8-fluoro-5-hydroxy-4-methyl-1H-quinolin-2-oneHCID 68785818—
Product2-[3-(2,4-dichlorobenzyl)-8-fluoro-4-methyl-2-oxo-1,2-dihydroquinolin-5-yloxy]propionic Acid Methyl EsterHCID 68780101—

Reaction Steps

The title compound was prepared by the method of Preparation 34d using 3-(2,4-dichlorobenzyl)-8-fluoro-5-hydroxy-4-methyl-1H-quinolin-2-one and 2-bromopropionic acid methyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07858640B2
Source datasetuspto-grants-2010_12
ORD IDord-0eee3c290e544df7b562858378def758
Source noteuspto-grants-2010_12