Methyl 2-bromopropionate → HCID 68782424, compound

HRID 2266613Notes

Reaction equation

HRID 2266613 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([OH:22])=[C:6]2[C:11]=1[NH:10][C:9](=[O:12])[C:8]([CH2:13][C:14]1[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][CH:15]=1)=[C:7]2[CH3:21].[CH3:23][O:24][C:25](=[O:29])[CH:26](Br)[CH3:27]>>[CH3:23][O:24][C:25](=[O:29])[CH:26]([O:22][C:5]1[CH:4]=[CH:3][C:2]([Cl:1])=[C:11]2[C:6]=1[C:7]([CH3:21])=[C:8]([CH2:13][C:14]1[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][CH:15]=1)[C:9](=[O:12])[NH:10]2)[CH3:27]

Participants

3

Reactant 2

HCID 95576Methyl 2-bromopropionateHCID 68783118HCID 68783118, compound

Product 1

HCID 68782424HCID 68782424, compound

Procedure

The title compound was prepared by the method of Preparation 34d using 8-chloro-3-(4-chlorobenzyl)-5-hydroxy-4-methyl-1H-quinolin-2-one and 2-bromopropionic acid methyl ester.

Sources & evidence

ORD record
ord-3cc88903c818421ca5ef1c962429b90a
Source dataset
uspto-grants-2010_12
Patent number
US07858640B2

Reaction notes

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