Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2266630Generated: October 25, 2026

(S)-2-(3-amino-4-fluorophenoxy)propionic acid methyl ester → (S)-2-[3-(2-chloro-4-cyclobutylcarbamoylbenzyl)-2-ethyl-8-fluoro-4-oxo-1,4-dihydroquinolin-5-yloxy]propionic Acid Methyl Ester

https://huagongshe.com/reaction/2266630

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-2-(3-amino-4-fluorophenoxy)propionic acid methyl esterHCID 66717596—
Reactant2-(2-chloro-4-cyclobutylcarbamoylbenzyl)-3-oxopentanoic Acid Ethyl EsterHCID 68782611—
Product(S)-2-[3-(2-chloro-4-cyclobutylcarbamoylbenzyl)-2-ethyl-8-fluoro-4-oxo-1,4-dihydroquinolin-5-yloxy]propionic Acid Methyl EsterHCID 68784731—

Reaction Steps

The title compound was prepared by the method of Preparation 65c using 2-(2-chloro-4-cyclobutylcarbamoylbenzyl)-3-oxopentanoic acid ethyl ester and (S)-2-(3-amino-4-fluorophenoxy)propionic acid methyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07858640B2
Source datasetuspto-grants-2010_12
ORD IDord-28a08cdc21da43d8a37c48fe4c875e78
Source noteuspto-grants-2010_12