Methanol → Methyl (benzylthio)acetate

HRID 2266772Notes

Reaction equation

HRID 2266772 reaction equation
[CH2:1]([S:8][CH2:9][C:10]([OH:12])=[O:11])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:13]O>>[CH2:1]([S:8][CH2:9][C:10]([O:12][CH3:13])=[O:11])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 887MethanolHCID 668972-((Phenylmethyl)thio)acetic acid

Product 1

HCID 562502Methyl (benzylthio)acetate

Procedure

S-benzylthioglycolic acid (12.0 g) was dissolved in 250 mL of methanol and sparged with hydrogen chloride gas at room temperature for 20 minutes. The solvent was then removed under vacuum. Methyl S-benzylthioglycolate obtained was used in the next step without further purification.

Workup

  1. customsparged with hydrogen chloride gas at room temperature for 20 minutes
  2. customThe solvent was then removed under vacuum

Sources & evidence

ORD record
ord-21269529c670422a9442a63999e16dab
Source dataset
uspto-grants-2010_12
Patent number
US07858664B2

Reaction notes

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