3-(Trifluoromethyl)phenylboronic acid → HCID 18444604, compound

HRID 2266828Notes

Reaction equation

HRID 2266828 reaction equation
I[C:2]1[CH:3]=[C:4]([CH:16]=[CH:17][CH:18]=1)[O:5][CH2:6][C:7]1[CH:8]=[C:9]([C:13]([OH:15])=[O:14])[O:10][C:11]=1[CH3:12].[F:19][C:20]([F:31])([F:30])[C:21]1[CH:22]=[C:23](B(O)O)[CH:24]=[CH:25][CH:26]=1>>[CH3:12][C:11]1[O:10][C:9]([C:13]([OH:15])=[O:14])=[CH:8][C:7]=1[CH2:6][O:5][C:4]1[CH:3]=[C:2]([C:25]2[CH:24]=[CH:23][CH:22]=[C:21]([C:20]([F:31])([F:30])[F:19])[CH:26]=2)[CH:18]=[CH:17][CH:16]=1

Participants

3

Reactant 2

HCID 27343883-(Trifluoromethyl)phenylboronic acidHCID 18444650HCID 18444650, compound

Product 1

HCID 18444604HCID 18444604, compound

Procedure

Compound (109) was prepared from compound (107) and (3-trifluoromethyl-phenyl)-boronic acid by adapting the procedure of Example 26A(c). LC/MS System B; Rt=1.97 mins, m/z (ES−)=375 (M−H for C20H15F3O4).

Sources & evidence

ORD record
ord-7686b072c89547759cabd1207c49bf6f
Source dataset
uspto-grants-2010_12
Patent number
US07858644B2

Reaction notes

Loading…