HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodine → HCID 11392086, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodine | HCID 807 | — |
| Reactant | 4-tert-Butylcatechol | HCID 7381 | — |
| Reactant | Sulfuric acid magnesium salt (1:1) | HCID 24083 | — |
| Reactant | tert-Butyl (4-aminophenyl)carbamate | HCID 688611 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 11392086 | HCID 11392086 | — |
Reaction Steps
A mixture of N-Boc-1,4-phenylenediamine (75 g), MgSO4 (216 g), 4-tert-butylcatechol (1.8 g) and iodine (4.7 g) in anhydrous acetone (600 ml) was refluxed for 20 h. The MgSO4 was removed by filtration and the filtrate was concentrated in vacuo. The residue was chromatographed on a short plug of silicagel using heptane/ethyl acetate=8/2 (v/v) as the eluent to give the product as a brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07858794B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-35feece179034cb4b92609be93157658 |
| Source note | uspto-grants-2010_12 |