Azidobenzene → HCID 58945818, compound

Participants

Reaction Conditions

Reaction Steps

The above-prepared phenyl azide (214 mg) and 200 mg of tert-butyl 4-(1-propynyl)-1,2,3,6-tetrahydropyridine-1-carboxylate prepared in 3) were dissolved in 3 ml of toluene and the solution was stirred at 120° C. for one night. The resulting solution was cooled down to room temperature, the solvent was evaporated in vacuo and the resulting residue was purified by a preparative thin-layer silica gel chromatography (hexane:ethyl acetate=2:1) to give 9.4 mg of the title compound as a white solid.

Provenance & Evidence