HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiophenol → 5,5-Dimethyl-1-(2-{4-[5-(phenylthio)thiophen-2-yl]pyrimidin-2-ylamino}ethyl)imidazolidine-2,4-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiophenol | HCID 7969 | — |
| Reactant | 1-{2-[4-(5-Iodothiophen-2-yl)pyrimidin-2-ylamino]ethyl}-5,5-dimethylimidazolidine-2,4-dione | HCID 60204465 | — |
| Product | 5,5-Dimethyl-1-(2-{4-[5-(phenylthio)thiophen-2-yl]pyrimidin-2-ylamino}ethyl)imidazolidine-2,4-dione | HCID 11683618 | — |
Reaction Steps
The title compound was prepared from 1-{2-[4-(5-iodothiophen-2-yl)pyrimidin-2-ylamino]ethyl}-5,5-dimethyl-imidazolidine-2,4-dione and thiophenol in a manner analogous to Example 259. MS (M+H)+ 440.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07858785B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-62abf681bcab42db8eefd583d09c2515 |
| Source note | uspto-grants-2010_12 |