HCID 59003341, compound → HCID 59003276, compound

Participants

Reaction Steps

To a solution of 5-[5-(hydroxymethyl)-2-thienyl]-3-(1-{[3-(4-morpholinyl)propyl]sulfonyl}-4-piperidinyl)-1H-indole-7-carboxamide (82.5 mg, 0.015 mmol) in THF (10 mL) was added MnO2 (391 mg, 4.5 mmol). The reaction mixture was stirred at room temperature overnight and filtered through a pad of celite after that. The filtrate was collected and concentrated at reduced pressure to give the crude product (60 mg, 73%), which was used in the next step without further purification.

Provenance & Evidence