Methylamine → HCID 11647883, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 3-[1-(ethenylsulfonyl)-4-piperidinyl]-5-phenyl-1H-indole-7-carboxamide (26 mg, 0.063 mmol) in CH3CN (1.0 mL), were added methylamine (19.5 mg, 0.63 mmol). The reaction solution was heated to 80° C. overnight. After which time the reaction mixture was purified by reverse phase HPLC (water/CH3CN, 0.1% TFA 10-90%) to give the title compound (15 mg, 54%).

Provenance & Evidence