HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methoxyphenol → HCID 59003294, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methoxyphenol | HCID 9015 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-{1-[(3-chloropropyl)sulfonyl]-4-piperidinyl}-5-phenyl-1H-indole-7-carboxamide | HCID 59003280 | — |
| Catalyst | Sodium Iodide | HCID 5238 | — |
| Product | HCID 59003294 | HCID 59003294 | 44.1% |
Reaction Steps
Following the general procedure of example 159, 3-{1-[(3-chloropropyl)sulfonyl]-4-piperidinyl}-5-phenyl-1H-indole-7-carboxamide (40.0 mg, 0.087 mmol), 4-(methyloxy)phenol (124 mg, 0.87 mmol), K2CO3 (35.0 mg, 0.35 mmol) and sodium iodide (0.5 mg) were reacted to give the title compound (21.0 mg, 44%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07858796B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-a6af0e3d59fb40a29b0ab5bb85dae1c0 |
| Source note | uspto-grants-2010_12 |