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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2267567Generated: November 2, 2026

Sodium Iodide → HCID 59003350, compound

https://huagongshe.com/reaction/2267567

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium IodideHCID 5238—
ReactantSodium HydroxideHCID 14798—
Reactant3-{1-[(3-chloropropyl)sulfonyl]-4-piperidinyl}-5-phenyl-1H-indole-7-carboxamideHCID 59003280—
SolventWaterHCID 962—
ProductHCID 59003350HCID 5900335068%

Reaction Steps

Following the general procedure of example 159, 3-{1-[(3-chloropropyl)sulfonyl]-4-piperidinyl}-5-phenyl-1H-indole-7-carboxamide (23.0 mg, 0.050 mmol), 50% NaOH in water (1 mL), and sodium iodide (5.0 mg) were reacted to give the title compound (15.0 mg, 68%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07858796B2
Source datasetuspto-grants-2010_12
ORD IDord-f81f2a880a334b0db2bb080834e698c7
Source noteuspto-grants-2010_12