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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2267726Generated: October 31, 2026

1-(2-(Azepan-1-yl)ethyl)piperidin-4-amine trihydrochloride → 4-Isopropoxy-1H-indole-2-carboxylic acid [1-(2-azepan-1-yl-ethyl)-piperidin-4-yl]-amide

https://huagongshe.com/reaction/2267726

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-(Azepan-1-yl)ethyl)piperidin-4-amine trihydrochlorideHCID 66841393—
Reactant4-Isopropoxy-1H-indole-2-carboxylic acidHCID 66841602—
Product4-Isopropoxy-1H-indole-2-carboxylic acid [1-(2-azepan-1-yl-ethyl)-piperidin-4-yl]-amideHCID 11154545—

Reaction Steps

This compound is synthesized analogously to Example 1 from 4-Isopropoxy-1H-indole-2-carboxylic acid 74 (preparation see below) and amine 5.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07858781B2
Source datasetuspto-grants-2010_12
ORD IDord-ac7eff5c145a47efa5fdf02a46e80d31
Source noteuspto-grants-2010_12