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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2267741Generated: October 30, 2026

4-Isobutoxy-1H-indole-2-carboxylic acid [1-(2-azepan-1-yl-ethyl)-piperidin-4-yl]-amide → 4-Isobutoxy-1H-indole-2-carboxylic acid {1-[2-(4-methyl-piperidin-1-yl)-ethyl]-piperidin-4-yl}-amide

https://huagongshe.com/reaction/2267741

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Isobutoxy-1H-indole-2-carboxylic acid [1-(2-azepan-1-yl-ethyl)-piperidin-4-yl]-amideHCID 11442047—
Reactant1-[2-(4-Methyl-piperidin-1-yl)-ethyl]-piperidin-4-ylamine tri-hydrochlorideHCID 66841322—
Product4-Isobutoxy-1H-indole-2-carboxylic acid {1-[2-(4-methyl-piperidin-1-yl)-ethyl]-piperidin-4-yl}-amideHCID 11259248—

Reaction Steps

This compound is synthesized analogously to Example 1 from 4-Isobutoxy-1H-indole-2-carboxylic acid 80 (preparation see Example 8) and amine 7.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07858781B2
Source datasetuspto-grants-2010_12
ORD IDord-b0be9d89f0cd406bb8dd021efb3601cb
Source noteuspto-grants-2010_12