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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2267743Generated: October 31, 2026

4-Isobutoxy-1H-indole-2-carboxylic acid [1-(2-azepan-1-yl-ethyl)-piperidin-4-yl]-amide → 4-Isobutoxy-1H-indole-2-carboxylic acid {1-[2-(4-hydroxy-piperidin-1-yl)-ethyl]-piperidin-4-yl}-amide

https://huagongshe.com/reaction/2267743

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Isobutoxy-1H-indole-2-carboxylic acid [1-(2-azepan-1-yl-ethyl)-piperidin-4-yl]-amideHCID 11442047—
ReactantHCID 66841786HCID 66841786—
Product4-Isobutoxy-1H-indole-2-carboxylic acid {1-[2-(4-hydroxy-piperidin-1-yl)-ethyl]-piperidin-4-yl}-amideHCID 11362737—

Reaction Steps

This compound is synthesized analogously to Example 1 from 4-Isobutoxy-1H-indole-2-carboxylic acid 80 (preparation see Example 8) and amine 21.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07858781B2
Source datasetuspto-grants-2010_12
ORD IDord-c1fe501e25ec41feb003d7f3870f1226
Source noteuspto-grants-2010_12