HCID 66841433, compound → HCID 11190308, compound

HRID 2267745Notes

Reaction equation

HRID 2267745 reaction equation
[CH2:1]([O:5][C:6]1[CH:14]=[CH:13][CH:12]=[C:11]2[C:7]=1[CH:8]=[C:9]([C:15]([OH:17])=O)[NH:10]2)[CH:2]([CH3:4])[CH3:3].Cl.Cl.Cl.[NH2:21][CH:22]1[CH2:27][CH2:26][N:25]([CH2:28][C@@H:29]([N:31]2[CH2:36][CH2:35][CH:34]([OH:37])[CH2:33][CH2:32]2)[CH3:30])[CH2:24][CH2:23]1>>[OH:37][CH:34]1[CH2:33][CH2:32][N:31]([C@@H:29]([CH3:30])[CH2:28][N:25]2[CH2:24][CH2:23][CH:22]([NH:21][C:15]([C:9]3[NH:10][C:11]4[C:7]([CH:8]=3)=[C:6]([O:5][CH2:1][CH:2]([CH3:3])[CH3:4])[CH:14]=[CH:13][CH:12]=4)=[O:17])[CH2:27][CH2:26]2)[CH2:36][CH2:35]1

Participants

3

Reactant 2

HCID 66841433HCID 66841433, compoundHCID 668416074-Isobutoxy-1H-indole-2-carboxylic acid

Product 1

HCID 11190308HCID 11190308, compound

Procedure

This compound is synthesized analogously to example 1 from 4-isobutoxy-1H-indole-2-carboxylic acid, 80 (see example 8) and amine 50.

Sources & evidence

ORD record
ord-0d731929628c40f3b7916fd5d1f285ab
Source dataset
uspto-grants-2010_12
Patent number
US07858781B2

Reaction notes

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