(4-Amino-benzyl)-methyl-(tetrahydro-pyran-4-yl)-amine → HCID 11419161, compound

HRID 2267747Notes

Reaction equation

HRID 2267747 reaction equation
N1(CCN2[CH2:15][CH2:14][CH:13]([NH:16][C:17]([C:19]3[NH:20][C:21]4[C:26]([CH:27]=3)=[C:25]([O:28][CH2:29][CH:30]([CH3:32])[CH3:31])[CH:24]=[CH:23][CH:22]=4)=[O:18])[CH2:12][CH2:11]2)CCCCCC1.NC1C=C[C:37]([CH2:38][N:39]([CH3:46])[CH:40]2[CH2:45][CH2:44][O:43][CH2:42][CH2:41]2)=CC=1>>[CH3:46][N:39]([CH2:38][C:37]1[CH:11]=[CH:12][C:13]([NH:16][C:17]([C:19]2[NH:20][C:21]3[C:26]([CH:27]=2)=[C:25]([O:28][CH2:29][CH:30]([CH3:31])[CH3:32])[CH:24]=[CH:23][CH:22]=3)=[O:18])=[CH:14][CH:15]=1)[CH:40]1[CH2:45][CH2:44][O:43][CH2:42][CH2:41]1

Participants

3

Reactant 2

HCID 9877845(4-Amino-benzyl)-methyl-(tetrahydro-pyran-4-yl)-amineHCID 114420474-Isobutoxy-1H-indole-2-carboxylic acid [1-(2-azepan-1-yl-ethyl)-piperidin-4-yl]-amide

Product 1

HCID 11419161HCID 11419161, compound

Procedure

This compound is synthesized analogously to Example 1 from 4-Isobutoxy-1H-indole-2-carboxylic acid 80 (preparation see Example 8) and (4-Amino-benzyl)-methyl-(tetrahydro-pyran-4-yl)-amine (WO9932468).

Sources & evidence

ORD record
ord-4afb5b3c099244719ae6e48b17f6faa8
Source dataset
uspto-grants-2010_12
Patent number
US07858781B2

Reaction notes

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