4-Isobutoxy-1H-indole-2-carboxylic acid [1-(2-azepan-1-yl-ethyl)-piperidin-4-yl]-amide → HCID 11374326, compound

HRID 2267748Notes

Reaction equation

HRID 2267748 reaction equation
N1(CCN2[CH2:15][CH2:14][CH:13]([NH:16][C:17]([C:19]3[NH:20][C:21]4[C:26]([CH:27]=3)=[C:25]([O:28][CH2:29][CH:30]([CH3:32])[CH3:31])[CH:24]=[CH:23][CH:22]=4)=[O:18])[CH2:12][CH2:11]2)CCCCCC1.Cl.Cl.NC1C=C[C:39]([C@H:42]([N:44]([CH3:51])[CH:45]2[CH2:50][CH2:49][O:48][CH2:47][CH2:46]2)[CH3:43])=CC=1>>[CH3:51][N:44]([CH:45]1[CH2:46][CH2:47][O:48][CH2:49][CH2:50]1)[C@@H:42]([C:43]1[CH:11]=[CH:12][C:13]([NH:16][C:17]([C:19]2[NH:20][C:21]3[C:26]([CH:27]=2)=[C:25]([O:28][CH2:29][CH:30]([CH3:31])[CH3:32])[CH:24]=[CH:23][CH:22]=3)=[O:18])=[CH:14][CH:15]=1)[CH3:39]

Participants

3

Reactant 2

HCID 114420474-Isobutoxy-1H-indole-2-carboxylic acid [1-(2-azepan-1-yl-ethyl)-piperidin-4-yl]-amideHCID 66841558HCID 66841558, compound

Product 1

HCID 11374326HCID 11374326, compound

Procedure

This compound is synthesized analogously to Example 1 from 4-Isobutoxy-1H-indole-2-carboxylic acid 80 (preparation see Example 8) and amine 72.

Sources & evidence

ORD record
ord-aa9d714290c7408981d19d40031d4bb3
Source dataset
uspto-grants-2010_12
Patent number
US07858781B2

Reaction notes

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