4-Cyclobutylmethoxy-1H-indole-2-carboxylic acid → HCID 59600181, compound

HRID 2267749Notes

Reaction equation

HRID 2267749 reaction equation
[CH:1]1([CH2:5][O:6][C:7]2[CH:15]=[CH:14][CH:13]=[C:12]3[C:8]=2[CH:9]=[C:10]([C:16]([OH:18])=O)[NH:11]3)[CH2:4][CH2:3][CH2:2]1.Cl.Cl.Cl.[N:22]1([CH2:29][CH2:30][N:31]2[CH2:36][CH2:35][CH:34]([NH2:37])[CH2:33][CH2:32]2)[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]1>>[N:22]1([CH2:29][CH2:30][N:31]2[CH2:32][CH2:33][CH:34]([NH:37][C:16]([C:10]3[NH:11][C:12]4[C:8]([CH:9]=3)=[C:7]([O:6][CH2:5][CH:1]3[CH2:2][CH2:3][CH2:4]3)[CH:15]=[CH:14][CH:13]=4)=[O:18])[CH2:35][CH2:36]2)[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]1

Participants

3

Reactant 2

HCID 591526824-Cyclobutylmethoxy-1H-indole-2-carboxylic acidHCID 668413931-(2-(Azepan-1-yl)ethyl)piperidin-4-amine trihydrochloride

Product 1

HCID 59600181HCID 59600181, compound

Procedure

This compound is synthesized analogously to Example 1 from 4-Cyclobutylmethoxy-1H-indole-2-carboxylic acid 82 (preparation see below) and amine 5.

Sources & evidence

ORD record
ord-b9b6a5a88b8c43da98d13708b1c34424
Source dataset
uspto-grants-2010_12
Patent number
US07858781B2

Reaction notes

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