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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2267753Generated: October 30, 2026

HCID 59600181, compound → 4-Cyclobutylmethoxy-1H-indole-2-carboxylic acid {1-[2-(3-(R)-hydroxy-piperidin-1-yl)-ethyl]-piperidin-4-yl}-amide

https://huagongshe.com/reaction/2267753

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 59600181HCID 59600181—
Reactant8-[2-(4-Amino-piperidin-1-yl)-ethyl]-8-aza-bicyclo[3.2.1]octan-3-ol trihydrochlorideHCID 66841574—
Product4-Cyclobutylmethoxy-1H-indole-2-carboxylic acid {1-[2-(3-(R)-hydroxy-piperidin-1-yl)-ethyl]-piperidin-4-yl}-amideHCID 59600131—

Reaction Steps

This compound is synthesized analogously to Example 1 from 4-Cyclobutylmethoxy-1H-indole-2-carboxylic acid 82 (preparation see Example 22) and amine 24.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07858781B2
Source datasetuspto-grants-2010_12
ORD IDord-0441a1e9996044c59349da59ce4760a0
Source noteuspto-grants-2010_12