4-Cyclopentylmethoxy-1H-indole-2-carboxylic acid → HCID 59600191, compound

HRID 2267757Notes

Reaction equation

HRID 2267757 reaction equation
[CH:1]1([CH2:6][O:7][C:8]2[CH:16]=[CH:15][CH:14]=[C:13]3[C:9]=2[CH:10]=[C:11]([C:17]([OH:19])=O)[NH:12]3)[CH2:5][CH2:4][CH2:3][CH2:2]1.Cl.Cl.Cl.[NH2:23][CH:24]1[CH2:29][CH2:28][N:27]([CH2:30][CH2:31][N:32]2[CH2:37][CH2:36][CH:35]([OH:38])[CH2:34][CH2:33]2)[CH2:26][CH2:25]1>>[OH:38][CH:35]1[CH2:34][CH2:33][N:32]([CH2:31][CH2:30][N:27]2[CH2:26][CH2:25][CH:24]([NH:23][C:17]([C:11]3[NH:12][C:13]4[C:9]([CH:10]=3)=[C:8]([O:7][CH2:6][CH:1]3[CH2:2][CH2:3][CH2:4][CH2:5]3)[CH:16]=[CH:15][CH:14]=4)=[O:19])[CH2:29][CH2:28]2)[CH2:37][CH2:36]1

Participants

3

Reactant 2

HCID 668411204-Cyclopentylmethoxy-1H-indole-2-carboxylic acidHCID 66841786HCID 66841786, compound

Product 1

HCID 59600191HCID 59600191, compound

Procedure

This compound is synthesized analogously to Example 1 from 4-Cyclopentylmethoxy-1H-indole-2-carboxylic acid 86 (preparation see below) and amine 21.

Sources & evidence

ORD record
ord-b86c4fe970394fb4af60199132e54f63
Source dataset
uspto-grants-2010_12
Patent number
US07858781B2

Reaction notes

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