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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2267762Generated: October 30, 2026

1-(2-(Azepan-1-yl)ethyl)piperidin-4-amine trihydrochloride → 4-(2,2-Dimethyl-propoxy)-1H-indole-2-carboxylic acid [1-(2-azepan-1-yl-ethyl)-piperidin-4-yl]-amide

https://huagongshe.com/reaction/2267762

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-(Azepan-1-yl)ethyl)piperidin-4-amine trihydrochlorideHCID 66841393—
Reactant4-(2,2-Dimethyl-propoxy)-1H-indole-2-carboxylic acidHCID 66841536—
Product4-(2,2-Dimethyl-propoxy)-1H-indole-2-carboxylic acid [1-(2-azepan-1-yl-ethyl)-piperidin-4-yl]-amideHCID 11316990—

Reaction Steps

This compound is synthesized analogously to Example 1 from 4-(2,2-Dimethyl-propoxy)-1H-indole-2-carboxylic acid 85 (preparation see below) and amine 5.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07858781B2
Source datasetuspto-grants-2010_12
ORD IDord-62e8e51fe8eb4ef186fe1e9142dfbc61
Source noteuspto-grants-2010_12