3,3-Dimethyl-1-butanol → 4-(3,3-dimethyl-butoxy)-1H-indole-2-carboxylic acid

HRID 2267768Notes

Reaction equation

HRID 2267768 reaction equation
CC(C)(C)CO[C:5]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:6]=1[CH:7]=[C:8]([C:14]([OH:16])=[O:15])[NH:9]2.[CH3:19][C:20]([CH3:25])([CH3:24])[CH2:21][CH2:22][OH:23]>>[CH3:19][C:20]([CH3:25])([CH3:24])[CH2:21][CH2:22][O:23][C:5]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:6]=1[CH:7]=[C:8]([C:14]([OH:16])=[O:15])[NH:9]2

Participants

3

Reactant 2

HCID 122333,3-Dimethyl-1-butanolHCID 668415364-(2,2-Dimethyl-propoxy)-1H-indole-2-carboxylic acid

Product 1

HCID 668415724-(3,3-dimethyl-butoxy)-1H-indole-2-carboxylic acid

Procedure

This compound is synthesized analogously to (85) from 3,3-dimethyl-butan-1-ol.

Sources & evidence

ORD record
ord-467f2429e351448bbe20ec5d2e28aefa
Source dataset
uspto-grants-2010_12
Patent number
US07858781B2

Reaction notes

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