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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2267772Generated: October 30, 2026

4-(furan-3-ylmethoxy)-1H-indole-2-carboxylic acid → 4-(Furan-3-ylmethoxy)-1H-indole-2-carboxylic acid [1-(2-azepan-1-yl-ethyl)-piperidin-4-yl]-amide

https://huagongshe.com/reaction/2267772

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(furan-3-ylmethoxy)-1H-indole-2-carboxylic acidHCID 59152651—
Reactant1-(2-(Azepan-1-yl)ethyl)piperidin-4-amine trihydrochlorideHCID 66841393—
Product4-(Furan-3-ylmethoxy)-1H-indole-2-carboxylic acid [1-(2-azepan-1-yl-ethyl)-piperidin-4-yl]-amideHCID 11488109—

Reaction Steps

This compound is synthesized analogously to Example 1 from 4-(furan-3-ylmethoxy)-1H-indole-2-carboxylic acid 95 (preparation see below) and amine 5.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07858781B2
Source datasetuspto-grants-2010_12
ORD IDord-4e18637b84864d7c8a1ff10c45dc6855
Source noteuspto-grants-2010_12