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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2267777Generated: November 3, 2026

4-(furan-3-ylmethoxy)-1H-indole-2-carboxylic acid → 4-(Furan-3-ylmethoxy)-1H-indole-2-carboxylic acid {1-[(S)-2-(4-hydroxy-piperidin-1-yl)-propyl]-piperidin-4-yl}-amide

https://huagongshe.com/reaction/2267777

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(furan-3-ylmethoxy)-1H-indole-2-carboxylic acidHCID 59152651—
Reactant1-[(S)-2-(4-Amino-piperidin-1-yl)-1-methyl-ethyl]-piperidin-4-ol trihydrochlorideHCID 66841433—
Product4-(Furan-3-ylmethoxy)-1H-indole-2-carboxylic acid {1-[(S)-2-(4-hydroxy-piperidin-1-yl)-propyl]-piperidin-4-yl}-amideHCID 11477166—

Reaction Steps

This compound is synthesized analogously to example 1 from 4-(furan-3-ylmethoxy)-1H-indole-2-carboxylic acid, 95 (see example 36) and amine 50.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07858781B2
Source datasetuspto-grants-2010_12
ORD IDord-32795ed582944b779010042043a043b2
Source noteuspto-grants-2010_12