HCID 66841564, compound → HCID 66841508, compound

HRID 2267780Notes

Reaction equation

HRID 2267780 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[O:9][CH:8]=[C:7]([CH2:10][O:11][C:12]3[CH:20]=[CH:19][CH:18]=[C:17]4[C:13]=3[CH:14]=[C:15]([C:21]([OH:23])=O)[NH:16]4)[C:6]=2[CH:24]=1.[ClH:25].Cl.Cl.[C@H:28]1([CH2:38][N:39]2[CH2:44][CH2:43][CH:42]([NH2:45])[CH2:41][CH2:40]2)[C@@H:37]2[N:32]([CH2:33][CH2:34][CH2:35][CH2:36]2)[CH2:31][CH2:30][CH2:29]1>>[ClH:1].[ClH:25].[C@H:28]1([CH2:38][N:39]2[CH2:44][CH2:43][CH:42]([NH:45][C:21]([C:15]3[NH:16][C:17]4[C:13]([CH:14]=3)=[C:12]([O:11][CH2:10][C:7]3[C:6]5[CH:24]=[C:2]([Cl:1])[CH:3]=[CH:4][C:5]=5[O:9][CH:8]=3)[CH:20]=[CH:19][CH:18]=4)=[O:23])[CH2:41][CH2:40]2)[C@@H:37]2[N:32]([CH2:33][CH2:34][CH2:35][CH2:36]2)[CH2:31][CH2:30][CH2:29]1

Participants

3

Reactant 2

HCID 66841564HCID 66841564, compoundHCID 66841583HCID 66841583, compound

Product 1

HCID 66841508HCID 66841508, compound

Procedure

This compound is synthesized from 4-(5-chloro-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid (97) (preparation see below) and amine 61 analogously to the method described in example 1.

Sources & evidence

ORD record
ord-4119cf72936c42bbbb201969fea7f1e5
Source dataset
uspto-grants-2010_12
Patent number
US07858781B2

Reaction notes

Loading…