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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2267792Generated: October 30, 2026

HCID 66841508, compound → 4-(5-Chloro-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid {1-[(S)-2-((3S,4S)-4-hydroxy-3-methyl-piperidin-1-yl)-propyl]-piperidin-4-yl}-amide dihydrochloride

https://huagongshe.com/reaction/2267792

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 66841508HCID 66841508—
Reactant(3S,4S)-1-[(S)-2-(4-Amino-piperidin-1-yl)-1-methyl-ethyl]-3-methyl-piperidin-4-ol tri-hydrochlorideHCID 66841745—
Product4-(5-Chloro-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid {1-[(S)-2-((3S,4S)-4-hydroxy-3-methyl-piperidin-1-yl)-propyl]-piperidin-4-yl}-amide dihydrochlorideHCID 66841683—

Reaction Steps

This compound is synthesized from 4-(5-chloro-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid (97, see example 42) and amine 56 analogously to the method described in example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07858781B2
Source datasetuspto-grants-2010_12
ORD IDord-a2f656e006094fabb9bdda88f0b14d2b
Source noteuspto-grants-2010_12