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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2267796Generated: October 31, 2026

4-(benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid → 4-(Benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid {1-[2-(4-hydroxy-piperidin-1-yl)-ethyl]-piperidin-4-yl}-amide

https://huagongshe.com/reaction/2267796

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acidHCID 59600130—
ReactantHCID 66841786HCID 66841786—
Product4-(Benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid {1-[2-(4-hydroxy-piperidin-1-yl)-ethyl]-piperidin-4-yl}-amideHCID 11156589—

Reaction Steps

This compound is synthesized analogously to example 1 from 4-(benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid, 105 (see example 50) and amine 21.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07858781B2
Source datasetuspto-grants-2010_12
ORD IDord-ec54255231a542528642978cede40e6a
Source noteuspto-grants-2010_12