4-(benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid → HCID 11283984, compound

HRID 2267798Notes

Reaction equation

HRID 2267798 reaction equation
[O:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[C:3]([CH2:10][O:11][C:12]2[CH:20]=[CH:19][CH:18]=[C:17]3[C:13]=2[CH:14]=[C:15]([C:21](O)=[O:22])[NH:16]3)=[CH:2]1.Cl.Cl.Cl.[NH2:27][CH:28]1[CH2:33][CH2:32][N:31]([CH2:34][C@@H:35]([N:37]2[CH2:42][CH2:41][CH:40]([OH:43])[CH2:39][CH2:38]2)[CH3:36])[CH2:30][CH2:29]1>>[OH:43][CH:40]1[CH2:39][CH2:38][N:37]([C@@H:35]([CH3:36])[CH2:34][N:31]2[CH2:30][CH2:29][CH:28]([NH:27][C:21]([C:15]3[NH:16][C:17]4[C:13]([CH:14]=3)=[C:12]([O:11][CH2:10][C:3]3[C:4]5[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=5[O:1][CH:2]=3)[CH:20]=[CH:19][CH:18]=4)=[O:22])[CH2:33][CH2:32]2)[CH2:42][CH2:41]1

Participants

3

Reactant 2

HCID 596001304-(benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acidHCID 66841433HCID 66841433, compound

Product 1

HCID 11283984HCID 11283984, compound

Procedure

This compound is synthesized analogously to example 1 from 4-(benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid, 105 (see example 50) and amine 50.

Sources & evidence

ORD record
ord-074c8fde2cb84026bd23f4cf178085b2
Source dataset
uspto-grants-2010_12
Patent number
US07858781B2

Reaction notes

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