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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2267800Generated: October 30, 2026

4-(6-fluoro-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid → 4-(6-Fluoro-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid {1-[(1S,9aR)-1-(octahydro-quinolizin-1-yl)methyl]-piperidin-4-yl}-amide dihydrochloride

https://huagongshe.com/reaction/2267800

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(6-fluoro-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acidHCID 66841531—
ReactantHCID 66841583HCID 66841583—
Product4-(6-Fluoro-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid {1-[(1S,9aR)-1-(octahydro-quinolizin-1-yl)methyl]-piperidin-4-yl}-amide dihydrochlorideHCID 66841596—

Reaction Steps

This compound is synthesized from 4-(6-fluoro-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid (106) (preparation see below) and amine 61 analogously to the method described in example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07858781B2
Source datasetuspto-grants-2010_12
ORD IDord-eb02db906c484c79a056638db14bff31
Source noteuspto-grants-2010_12