1-[(S)-2-(4-Amino-piperidin-1-yl)-1-methyl-ethyl]-piperidin-4-ol trihydrochloride → 4-(6-Chloro-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid {1-[(S)-2-(4-hydroxy-piperidin-1-yl)-propyl]-piperidin-4-yl}-amide dihydrochloride

Participants

Role	Name	HCID	Charge
Reactant	1-[(S)-2-(4-Amino-piperidin-1-yl)-1-methyl-ethyl]-piperidin-4-ol trihydrochloride	HCID 66841433	—
Reactant	HCID 66841909	HCID 66841909	—
Product	4-(6-Chloro-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid {1-[(S)-2-(4-hydroxy-piperidin-1-yl)-propyl]-piperidin-4-yl}-amide dihydrochloride	HCID 66841708	—

Reaction Steps

This compound is synthesized from 4-(6-chloro-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid (117, see example 72) and amine 50 analogously to the method described in example 1.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07858781B2
Source dataset	uspto-grants-2010_12
ORD ID	ord-47c6c618896047af93ddb6f2383b3a11
Source note	uspto-grants-2010_12