4-(7-methoxy-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid → 4-(7-Methoxy-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid {1-[(S)-2-((3S,4S)-4-hydroxy-3-methyl-piperidin-1-yl)-propyl]-piperidin-4-yl}-amide

Participants

Role	Name	HCID	Charge
Reactant	4-(7-methoxy-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid	HCID 66841593	—
Reactant	(3S,4S)-1-[(S)-2-(4-Amino-piperidin-1-yl)-1-methyl-ethyl]-3-methyl-piperidin-4-ol tri-hydrochloride	HCID 66841745	—
Product	4-(7-Methoxy-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid {1-[(S)-2-((3S,4S)-4-hydroxy-3-methyl-piperidin-1-yl)-propyl]-piperidin-4-yl}-amide	HCID 11180669	—

Reaction Steps

This compound is synthesized analogously to example 1 from 4-(7-methoxy-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid, 119 (see example 80) and amine 56.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07858781B2
Source dataset	uspto-grants-2010_12
ORD ID	ord-eb1ca3cbe72049f9838601f2f87a4afa
Source note	uspto-grants-2010_12