1-(2-(Azepan-1-yl)ethyl)piperidin-4-amine trihydrochloride → HCID 11203584, compound

HRID 2267841Notes

Reaction equation

HRID 2267841 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]2[O:10][CH:9]=[C:8]([CH2:11][O:12][C:13]3[CH:21]=[CH:20][CH:19]=[C:18]4[C:14]=3[CH:15]=[C:16]([C:22]([OH:24])=O)[NH:17]4)[C:7]=2[CH:25]=1.Cl.Cl.Cl.[N:29]1([CH2:36][CH2:37][N:38]2[CH2:43][CH2:42][CH:41]([NH2:44])[CH2:40][CH2:39]2)[CH2:35][CH2:34][CH2:33][CH2:32][CH2:31][CH2:30]1>>[N:29]1([CH2:36][CH2:37][N:38]2[CH2:39][CH2:40][CH:41]([NH:44][C:22]([C:16]3[NH:17][C:18]4[C:14]([CH:15]=3)=[C:13]([O:12][CH2:11][C:8]3[C:7]5[CH:25]=[C:3]([O:2][CH3:1])[CH:4]=[CH:5][C:6]=5[O:10][CH:9]=3)[CH:21]=[CH:20][CH:19]=4)=[O:24])[CH2:42][CH2:43]2)[CH2:35][CH2:34][CH2:33][CH2:32][CH2:31][CH2:30]1

Participants

3

Reactant 2

HCID 668413931-(2-(Azepan-1-yl)ethyl)piperidin-4-amine trihydrochlorideHCID 66842032HCID 66842032, compound

Product 1

HCID 11203584HCID 11203584, compound

Procedure

This compound is synthesized from 4-(5-methoxy-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid (121) (preparation see below) and amine 5 analogously to the method described in example 1.

Sources & evidence

ORD record
ord-df6baa5276b745519870de2ba72f1ec6
Source dataset
uspto-grants-2010_12
Patent number
US07858781B2

Reaction notes

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