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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2267849Generated: October 29, 2026

4-(4-methoxy-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid → 4-(4-Methoxy-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid {1-[(S)-2-(4-hydroxy-piperidin-1-yl)-propyl]-piperidin-4-yl}-amide

https://huagongshe.com/reaction/2267849

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-methoxy-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acidHCID 66841369—
ReactantHCID 66841433HCID 66841433—
Product4-(4-Methoxy-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid {1-[(S)-2-(4-hydroxy-piperidin-1-yl)-propyl]-piperidin-4-yl}-amideHCID 11455766—

Reaction Steps

This compound is synthesized analogously to example 1 from 4-(4-methoxy-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid, 122 (see example 94) and amine 50.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07858781B2
Source datasetuspto-grants-2010_12
ORD IDord-055240f58b3a42ecb1ee2098fd71e325
Source noteuspto-grants-2010_12