1-(2-(Azepan-1-yl)ethyl)piperidin-4-amine trihydrochloride → HCID 59600230, compound

HRID 2267877Notes

Reaction equation

HRID 2267877 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:18]=[CH:19][CH:20]=1)[O:5][C:6]1[CH:14]=[CH:13][CH:12]=[C:11]2[C:7]=1[CH:8]=[C:9]([C:15]([OH:17])=O)[NH:10]2.Cl.Cl.Cl.[N:24]1([CH2:31][CH2:32][N:33]2[CH2:38][CH2:37][CH:36]([NH2:39])[CH2:35][CH2:34]2)[CH2:30][CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1>>[N:24]1([CH2:31][CH2:32][N:33]2[CH2:34][CH2:35][CH:36]([NH:39][C:15]([C:9]3[NH:10][C:11]4[C:7]([CH:8]=3)=[C:6]([O:5][C:4]3[CH:18]=[CH:19][CH:20]=[C:2]([F:1])[CH:3]=3)[CH:14]=[CH:13][CH:12]=4)=[O:17])[CH2:37][CH2:38]2)[CH2:30][CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1

Participants

3

Reactant 2

HCID 668413931-(2-(Azepan-1-yl)ethyl)piperidin-4-amine trihydrochlorideHCID 66841616HCID 66841616, compound

Product 1

HCID 59600230HCID 59600230, compound

Procedure

This compound is synthesized analogously to Example 1 from 4-(3-Fluoro-phenoxy)-1H-indole-2-carboxylic acid 141 (preparation see below) and amine 5.

Sources & evidence

ORD record
ord-26a948ff06e7454485051ad464f9584d
Source dataset
uspto-grants-2010_12
Patent number
US07858781B2

Reaction notes

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