HCID 66841437, compound → HCID 59600235, compound

HRID 2267913Notes

Reaction equation

HRID 2267913 reaction equation
OC1C(O)CCN(C(C)[CH2:10][N:11]2[CH2:16][CH2:15][CH:14]([NH:17][C:18]([C:20]3[NH:21][C:22]4[C:27]([CH:28]=3)=[C:26]([O:29][CH2:30][C:31]3[C:35]5[CH:36]=[C:37]([Cl:40])[CH:38]=[CH:39][C:34]=5[O:33][CH:32]=3)[CH:25]=[CH:24][CH:23]=4)=[O:19])[CH2:13][CH2:12]2)C1.[CH2:42]1[CH:47]2[CH:48](CO)[CH2:49][CH2:50][CH2:51][N:46]2[CH2:45][CH2:44][O:43]1>>[CH2:42]1[C@@H:47]2[C@H:48]([CH2:10][N:11]3[CH2:16][CH2:15][CH:14]([NH:17][C:18]([C:20]4[NH:21][C:22]5[C:27]([CH:28]=4)=[C:26]([O:29][CH2:30][C:31]4[C:35]6[CH:36]=[C:37]([Cl:40])[CH:38]=[CH:39][C:34]=6[O:33][CH:32]=4)[CH:25]=[CH:24][CH:23]=5)=[O:19])[CH2:13][CH2:12]3)[CH2:49][CH2:50][CH2:51][N:46]2[CH2:45][CH2:44][O:43]1

Participants

3

Reactant 2

HCID 66841437HCID 66841437, compoundHCID 66841441HCID 66841441, compound

Product 1

HCID 59600235HCID 59600235, compound

Procedure

This compound is synthesized from the compound 176 (see example 138) and (9RS,9aSR)-1-(octahydro-pyrido[2,1-c][1,4]oxazin-9-yl)-methanol (63) analogously to the method described in example 127.

Sources & evidence

ORD record
ord-9f229333fa3044738decd1a3c16bfcc9
Source dataset
uspto-grants-2010_12
Patent number
US07858781B2

Reaction notes

Loading…