4-Aminophenethyl alcohol → HCID 66841637, compound

HRID 2267932Notes

Reaction equation

HRID 2267932 reaction equation
Cl.Cl.[C@H]1(CN2C[CH2:18][CH:17]([NH:20][C:21]([C:23]3[NH:24][C:25]4[C:30]([CH:31]=3)=[C:29]([O:32][CH2:33][C:34]3[C:38]5[CH:39]=[C:40]([Cl:43])[CH:41]=[CH:42][C:37]=5[O:36][CH:35]=3)[CH:28]=[CH:27][CH:26]=4)=[O:22])[CH2:16][CH2:15]2)[C@@H]2N(CCCC2)CCC1.NC1C=C[C:48]([CH2:51][CH2:52][OH:53])=[CH:47]C=1>>[OH:53][CH2:52][CH2:51][C:48]1[CH:15]=[CH:16][C:17]([NH:20][C:21]([C:23]2[NH:24][C:25]3[C:30]([CH:31]=2)=[C:29]([O:32][CH2:33][C:34]2[C:38]4[CH:39]=[C:40]([Cl:43])[CH:41]=[CH:42][C:37]=4[O:36][CH:35]=2)[CH:28]=[CH:27][CH:26]=3)=[O:22])=[CH:18][CH:47]=1

Participants

3

Reactant 2

HCID 669044-Aminophenethyl alcoholHCID 66841508HCID 66841508, compound

Product 1

HCID 66841637HCID 66841637, compound

Procedure

This compound is synthesized analogously to example 42 from 4-(5-Chloro-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid (97) and 2-(4-amino-phenyl)-ethanol.

Sources & evidence

ORD record
ord-2299511f26be4c40aad5d9471661feb1
Source dataset
uspto-grants-2010_12
Patent number
US07858781B2

Reaction notes

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