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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2267949Generated: October 29, 2026

4-Isobutoxy-benzo[b]thiophene-2-carboxylic acid → 4-Isobutoxy-benzo[b]thiophene-2-carboxylic acid [1-(2-azepan-1-yl-ethyl)-piperidin-4-yl]-amide

https://huagongshe.com/reaction/2267949

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Isobutoxy-benzo[b]thiophene-2-carboxylic acidHCID 59600259—
Reactant1-(2-(Azepan-1-yl)ethyl)piperidin-4-amine trihydrochlorideHCID 66841393—
Product4-Isobutoxy-benzo[b]thiophene-2-carboxylic acid [1-(2-azepan-1-yl-ethyl)-piperidin-4-yl]-amideHCID 59600120—

Reaction Steps

This compound is synthesized from compound 202 and amine 5 analogously to the method described in Example 178.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07858781B2
Source datasetuspto-grants-2010_12
ORD IDord-f6a91b36a5904940a1c702ec20926112
Source noteuspto-grants-2010_12