ethyl 4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate → HCID 18348795, compound

HRID 2268046Notes

Reaction equation

HRID 2268046 reaction equation
C([O:3][C:4]([C:6]1[C:7](Cl)=[C:8]2[CH:14]=[N:13][N:12]([CH2:15][CH3:16])[C:9]2=[N:10][CH:11]=1)=[O:5])C.[O:18]=[C:19]=[C:20]1[C:25](=[C:26]=[O:27])[CH:24]=[CH:23][C:22]([CH2:28][NH2:29])=[CH:21]1>>[O:18]=[C:19]=[C:20]1[C:25](=[C:26]=[O:27])[CH:24]=[CH:23][C:22]([CH2:28][NH:29][C:7]2[C:6]([C:4]([OH:3])=[O:5])=[CH:11][N:10]=[C:9]3[N:12]([CH2:15][CH3:16])[N:13]=[CH:14][C:8]=23)=[CH:21]1

Participants

3

Reactant 2

HCID 10491120ethyl 4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylateHCID 18348779HCID 18348779, compound

Product 1

HCID 18348795HCID 18348795, compoundYield 80%

Procedure

4-Chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester and (3,4-dioxomethylenephenyl)methylamine were used to afford the title compound (80%) as a white solid: mp 230° C. (decomposed).

Sources & evidence

ORD record
ord-7d062bbf512b4b5b9b332b6e4e9b1ee5
Source dataset
uspto-grants-2001_12
Patent number
US06326379B1

Reaction notes

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