Potassium Sodium Tartrate → HCID 69836284, compound

Participants

Reaction Conditions

Reaction Steps

0.9 g of (E)-3-(3,5-di-tert.-butyl-2-butyloxyphenyl)-butenoic acid ethyl ester was dissolved in 20 ml of dry ether. This was cooled to −78° C. and treated with 6.0 ml of diisobutylaluminum hydride (1.0M in hexane). The temperature was allowed to warm to 0° C. and was then treated with 20% aqueous Rochelle salt. This was stirred at 25° C. for 1 hr. The organic fraction was separated, washed with water, dried (Na2SO4), and had solvent removed to give 0.78 g of (Z)-3-(3,5-di-tert.-butyl-2-butyloxyphenyl)-buten-1-ol. 1H NMR (CDCl3) δ 7.08 (dd, 4H, aromatics), 5.90 (t, 1H, CH—OH), 3.80 (t, 2H, —OCH2—), 2.49 (t, 1H, —OH), 2.21 (s, 3H).

Provenance & Evidence