Acetone → 4-(2,2-Dimethyl-1,3-dioxolan-4-yl)butan-1-ol

HRID 2268129Notes

Reaction equation

HRID 2268129 reaction equation
[CH2:1]([OH:9])[CH:2]([OH:8])[CH2:3][CH2:4][CH2:5][CH2:6][OH:7].[CH3:10][C:11]([CH3:13])=O>>[CH3:10][C:11]1([CH3:13])[O:8][CH:2]([CH2:3][CH2:4][CH2:5][CH2:6][OH:7])[CH2:1][O:9]1

Participants

3

Reactant 2

HCID 180AcetoneHCID 78231,2,6-Hexanetriol

Product 1

HCID 2366824-(2,2-Dimethyl-1,3-dioxolan-4-yl)butan-1-ol

Procedure

15 g (112 mmol) of 1,2,6-hexanetriol were dissolved together with 0.5 g of FeCl3 in 1 1 of acetone and boiled under reflux for 7 h. The mixture was filtered, and excess acetone was removed by distillation, resulting in the product in pure form.

Workup

  1. temperatureunder reflux for 7 h
  2. filtrationThe mixture was filtered
  3. customexcess acetone was removed by distillation
  4. customresulting in the product in pure form

Sources & evidence

ORD record
ord-9d69088190034bc19881fe47f9f5b1e1
Source dataset
uspto-grants-2001_12
Patent number
US06326487B1

Reaction notes

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