HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methoxyphenol → HCID 18349474, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methoxyphenol | HCID 9015 | — |
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | ethyl N-ethoxycarbonyliminocarbamate | HCID 220568 | — |
| Reactant | 4-(2,2-Dimethyl-1,3-dioxolan-4-yl)butan-1-ol | HCID 236682 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 18349474 | HCID 18349474 | — |
Reaction Steps
1.74 g (10 mmol) of 2,2-dimethyl-4-hydroxybutyl-1,3-dioxolane from Example 1a, 3.41 g (13 mmol) of triphenylphosphine, 2.26 g (13 mmol) of diethyl azodicarboxylate and 3.72 g (30 mmol) of 4-methoxyphenol were dissolved in 30 ml of absolute tetrahydrofuran (THF) and boiled under reflux for 1 h. The solvent was removed by distillation, and the residue was chromatographed on silica gel using ethyl acetate (EA)/n-heptane (1:4).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06326487B1 |
| Source dataset | uspto-grants-2001_12 |
| ORD ID | ord-c3ec53a984954ad2b25cf8222d8cb52a |
| Source note | uspto-grants-2001_12 |