HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2268148Generated: October 30, 2026
3-Methoxy-2-pyridone → HCID 66647628, compound
https://huagongshe.com/reaction/2268148
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-Methoxy-2-pyridone | HCID 88731 | — |
| Reactant | 3-Methoxy-1-(4-methoxybenzyl)-4-propionyl-5,6-dihydro-1H-pyridin-2-one | HCID 11197437 | — |
| Reactant | Cyclopentylhydrazinato--hydrogen chlorido (1/2) | HCID 18349526 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 66647628 | HCID 66647628 | — |
Reaction Steps
treating said 3-methoxy-pyridinone compound of Formula (7.0.0) with cyclopentylhydrazine dihydrochloride; wherein a reaction mixture is established with tetrahydrofuran (THF) solvent and heating of said reaction mixture to 88° C., for 12 hours, while said reaction mixture is being swept by nitrogen in order to remove methanol, THF, and HCl; whereby there is produced a pyrazolopyridinone compound N-protected by p-methoxybenzyl, of Formula (8.0.0):
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06326495B2 |
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| Source dataset | uspto-grants-2001_12 |
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| ORD ID | ord-6123e3976c2e48e09cad5b6ce8e8e4fe |
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| Source note | uspto-grants-2001_12 |
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