反应详情

1.7 g (3.7 mmol) of benzyl 4-[3-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)acryloyloxy]-benzoate, 40 ml of dioxane and 340 mg of palladium on charcoal (10%) are introduced into a reactor. The mixture is hydrogenated at 40° C. and at a pressure of 7 bar for three hours. The catalyst is filtered off and the mixture is evaporated to dryness. The solid obtained is triturated from hexane, filtered off and dried. 1.2 g (85%) of 4-[3-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)propanoyloxy]benzoic acid, with a melting point of 183-4° C., are collected.

1. filtrationThe catalyst is filtered off
2. customthe mixture is evaporated to dryness
3. customThe solid obtained
4. customis triturated from hexane
5. filtrationfiltered off
6. customdried
7. custom1.2 g (85%) of 4-[3-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)propanoyloxy]benzoic acid, with a melting point of 183-4° C., are collected