tert-Butyl 4-hydroxybenzoate → HCID 70215749, compound

HRID 2268215Notes

Reaction equation

HRID 2268215 reaction equation
[CH3:1][C:2]1([CH3:19])[CH2:11][CH2:10][C:9]([CH3:13])([CH3:12])[C:8]2[CH:7]=[C:6]([C:14]#[C:15][C:16](Cl)=[O:17])[CH:5]=[CH:4][C:3]1=2.[OH:20][C:21]1[CH:33]=[CH:32][C:24]([C:25]([O:27][C:28]([CH3:31])([CH3:30])[CH3:29])=[O:26])=[CH:23][CH:22]=1>>[CH3:1][C:2]1([CH3:19])[CH2:11][CH2:10][C:9]([CH3:13])([CH3:12])[C:8]2[CH:7]=[C:6]([C:14]#[C:15][C:16]([O:20][C:21]3[CH:33]=[CH:32][C:24]([C:25]([O:27][C:28]([CH3:29])([CH3:30])[CH3:31])=[O:26])=[CH:23][CH:22]=3)=[O:17])[CH:5]=[CH:4][C:3]1=2

Participants

3

Reactant 2

HCID 117640tert-Butyl 4-hydroxybenzoateHCID 86757636HCID 86757636, compound

Product 1

HCID 70215749HCID 70215749, compound

Procedure

In a similar manner to that of Example 1(d), by reaction of 1.4 g (5 mmol) of 3-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)propynoyl chloride with 950 mg (4.9 mmol) of tert-butyl 4-hydroxybenzoate, 1.75 g (83%) of the expected tert-butyl ester are obtained in the form of a yellow oil.

Workup

  1. customare obtained in the form of a yellow oil

Sources & evidence

ORD record
ord-6952180056074840ae955c3741982daa
Source dataset
uspto-grants-2001_12
Patent number
US06326510B1

Reaction notes

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