N-[1-(4'-Benzyloxybiphenyl-4-yl)-1-methylethyl]-3-(imidazol-1-yl)propylamine → 4'-{1-[3-(Imidazol-1-yl)propylamino]-1-methylethyl}biphenyl-4-ol
반응식
C([O:8][C:9]1[CH:14]=[CH:13][C:12]([C:15]2[CH:20]=[CH:19][C:18]([C:21]([NH:24][CH2:25][CH2:26][CH2:27][N:28]3[CH:32]=[CH:31][N:30]=[CH:29]3)([CH3:23])[CH3:22])=[CH:17][CH:16]=2)=[CH:11][CH:10]=1)C1C=CC=CC=1>[Pd]>[N:28]1([CH2:27][CH2:26][CH2:25][NH:24][C:21]([C:18]2[CH:19]=[CH:20][C:15]([C:12]3[CH:11]=[CH:10][C:9]([OH:8])=[CH:14][CH:13]=3)=[CH:16][CH:17]=2)([CH3:23])[CH3:22])[CH:32]=[CH:31][N:30]=[CH:29]1참가 물질
3
실험 절차
N-[1-(4′-Benzyloxybiphenyl-4-yl)-1-methylethyl]-3-(imidazol-1-yl)propylamine was hydrogenated, using palladium on charcoal as catalyst, in IMS at atmospheric pressure to give 4′-{1-[3-(imidazol-1-yl)propylamino]-1methylethyl}biphenyl-4-ol, m.p. 178-180° C.
출처 및 근거
- ORD 기록
- ord-8cbf2c4b5a2d4d228a3e775e8dbc1e6c
- 출처 데이터셋
- uspto-grants-2001_12
- 특허 번호
- US06326500B1
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