Triethylamine → HCID 10282993, compound

Participants

Reaction Steps

The title compound was prepared by a similar method to example 3 using (2R,3R,4S,5R)-2-{2-(aminomethyl)-6-[(2,2-diphenylethyl)amino}-9H-purin-9-yl}-5-(methoxymethyl)tetrahydro-3,4-furandiol (example 1) (265 mg, 0.54 mmol), phenylmethanesulfonyl chloride (98 mg, 0.51 mmol) and triethylamine (185 mg, 1.83 mmol) in dry tetrahydrofuran (23 ml). This gave the title compound (240 mg) as a gum. MS: 645 (MH+).

Provenance & Evidence