HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium methanethiolate → 2-(Methylsulfanyl)-N-phenethyl-9-tetrahydro-2H-pyran-2-yl-9H-purin-6-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium methanethiolate | HCID 4378561 | — |
| Reactant | 2-Chloro-N-phenethyl-9-tetrahydro-2H-pyran-2-yl-9H-purin-6-amine | HCID 20709184 | — |
| Product | 2-(Methylsulfanyl)-N-phenethyl-9-tetrahydro-2H-pyran-2-yl-9H-purin-6-amine | HCID 20709189 | 92.2% |
Reaction Steps
The title compound was prepared by a similar method to preparation 7 from 2-chloro-N-phenethyl-9-tetrahydro-2H-pyran-2-yl-9H-purin-6-amine (17.5 g, 49 mmol) (preparation 41) and sodium thiomethoxide (7.2 g, 75 mmol). This gave the title compound (16.7 g) as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06326359B1 |
| Source dataset | uspto-grants-2001_12 |
| ORD ID | ord-56ed36503f044b758edc202cf67bc883 |
| Source note | uspto-grants-2001_12 |