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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 226877Generated: October 25, 2026

Diisopropylethylamine → HCID 22060999, compound

https://huagongshe.com/reaction/226877

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisopropylethylamineHCID 81531—
Reactant4-Amino-M-cresol hydrochlorideHCID 459234—
Reactant2-chloro-5-fluoro-N-(3,4-ethylenedioxyphenyl)-4-pyrimidineamineHCID 22060362—
ProductHCID 22060999HCID 22060999—

Reaction Steps

In like manner to the preparation of 5-fluoro-N4-(3-hydroxyphenyl)-N2-[4-(3-phenyl-1,2,4-oxadiazol-5-yl)methyleneoxyphenyl]-2,4-pyrimidinediamine, 2-chloro-N4-(3,4-ethylenedioxyphenyl)-5-fluoro-4-pyrimidineamine, 4-amino-m-cresol hydrogenchloride salt, and diisopropylethylamine were reacted to provide N4-(3,4-ethylenedioxyphenyl)-5-fluoro-N4-(3-hydroxy-5-methylphenyl)-2,4-pyrimidinediamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07557210B2
Source datasetuspto-grants-2009_07
ORD IDord-bdf93c1943054f8d8b2abf3bc7ba4e19
Source noteuspto-grants-2009_07